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The following selection of reprints are available on request from GTC. Book Chapters: Gavin, W., L. Chen, D. Melican, C. Ziomek, Y. Echelard and H. Meade (2008). Transgenic cloned goats and cows for the production of therapeutic proteins in Principles of Regenerative Medicine. Academic Press. Behboodi, E., L. Chen, M. Destrempes, H.M. Meade and Y. Echelard (2002). Transgenic cloned goats and the production of therapeutic proteins. in Principles of Cloning. Elsevier Science (USA). Meade, H.M., Y. Echelard, C.A. Ziomek, M.W. Young, M. Harvey, E.S. Cole, S. Groet, T.E. Smith and J.M. Curling. (1999). Expression of recombinant proteins in the milk of transgenic animals. in Gene expression systems: using nature for the art of expression. J. M. Fernandez and J. P. Hoeffler ed., Academic Press. Echelard, Y. (1997). Genetic mosaicism in the generation of transgenic mice. in Transgenic animals - generation and use. L.M. Houdebine ed., Harwood Academic Publishers gmbh. Gavin, W.G., (1997). Gene transfer into goat embryos. in Transgenic animals - generation and use. L.M. Houdebine ed., Harwood Academic Publishers gmbh.   Articles: Melican, D. and W. Gavin (2008). Repeat superovulation, non-surgical embryo recovery, and surgical embryo transfer in transgenic dairy goats. Theriogenology. 69: 197-203. Echelard, Y., C.A. Ziomek and H.M. Meade (2006). Production of recombinant therapeutic proteins in the milk of transgenic animals. BioPharm International. 19: 36-46. He, S., D. Pant, A. Schiffmacher, S. Bischoff, D. Melican, W. Gavin and C.L. Keefer (2006). Developmental expression of pluripotency determining factors in caprine embryos: Novel pattern of NANOG protein localization in the nucleolus. Molecular Reproduction and Development. 73:1512-1522. Jellerette, T., D. Melican, R. Butler, S. Nims, C. Ziomek, R. Fissore and W. Gavin (2006). Characterization of calcium oscillation patterns in caprine oocytes induced by IVF or an activation technique used in nuclear transfer. Theriogenology. 65:1575-1586. Avidan, MD, M.S., J.H. Levy, MD, H. van Aken, MD, R.O. Feneck, MD, R.D. Latimer, MD, E. Ott, MD, E. Martin, MD, D.E. Birnbaum, MD, L.J. Bonfiglio, BSN, CRNA, D.K. Kajdasz, PhD and G.J. Despotis, MD (2005). Recombinant human antithrombin III restores heparin responsiveness and decreases activation of coagulation in heparin-resistant patients during cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery. 130:107-113. Avidan, M.S., J.H. Levy, J. Scholz, E. Delphin, P.M.J. Rosseel, M.B. Howie, I. Gratz, C.R. Bush, N. Skubas, G.S. Aldea, M. Licina, L.J. Bonfiglio, D.K. Kajdasz, E. Ott and G.J. Despotis (2005). A Phase III, double-blind, placebo-controlled, multicenter study on the efficacy of recombinant human antithrombin in heparin-resistant patients scheduled to undergo cardiac surgery necessitating cardiopulmonary bypass. Anesthesiology. 102:276-284. Blash, S., L. Chen, M. Harvey, and W. Gavin (2005). Reestablishment of a transgenic rabbit line by artificial insemination using cryopreserved semen. Lab Animal. 34:61-63. Cozzi, E., P. Simioni, M. Boldrin, M. Seveso, F. Calabrese, N. Baldan, R. Busetto, D. Tormene, S. Gavasso, M. Castagnaro, Y. Echelard, T. Rice, M. Plebani, P. Carraro, E. Bosio, M. Valente, A. Pagnan, G. Thiene and E. Ancona (2005). Effects of Long-term Administration of High-dose Recombinant Human Antithrombin in Immunosuppressed Primate Recipients of Porcine Xenografts. Transplantation. 80(10):1501-1510. Echelard, Y., H. Meade and C. Ziomek (2005). The First Biopharmaceutical from Transgenic Animals: ATryn®. Modern Biopharmaceuticals. WILEY-VCH Verlag GmbH & Co. KGaA; Kap. 4-11: 995-1016. Landry, A.M., D.J. Landry, L.R. Gentry, H.L.Green, B. Reggio, K.L. Koonce, Y. Echelard and R.A. Godke (2005). Endocrine Profiles and Growth Patterns of Cloned Goats. Cloning and Stem Cells. 7:214-225. Melican, D., R. Butler, N. Hawkins, L.H. Chen, E. Hayden, M. Destrempes, J. Williams, T. Lewis, E. Behboodi, C. Ziomek, H. Meade, Y. Echelard and W. Gavin (2005). Effect of serum concentration, method of trypsinization and fusion/activation utilizing transfected fetal cells to generate transgenic dairy goats by somatic cell nuclear transfer. Theriogenology. 63:1549-1563. Zhou, Q., J. Kyazike, Y. Echelard, H.M. Meade, E. Higgins, E.S. Cole and T. Edmunds (2005). Effect of genetic background on glycosylation heterogeneity in human antithrombin produced in the mammary gland of transgenic goats. J. Biotechnology. 117:57-72. Behboodi, E., E. Memili, D.T. Melican, M.M. Destrempes, S.A. Overton, J.L. Williams, P.A. Flanagan, R.E.Butler, H. Liem, L.H.Chen, H.M. Meade, W.G.Gavin and Y. Echelard (2004). Viable transgenic goats derived from skin cells. Transgenic Research. 13:215-224. Herrick, J.R., E. Behboodi, E. Memili, S. Blash, Y. Echelard and R.L. Krisher (2004). Effect of macromolecule supplementation during in vitro maturation of goat oocytes on developmental potential. Molecular Reproduction and Development. 69:338-346. Memili, E., E. Behboodi, S.A. Overton, A.M. Kenney, M. O'Coin, A. Zahedi, D.H. Rowitch and Y. Echelard (2004). Synchronization of goat fibroblast cells at quiescent stage and determination of their transition from GO and G1 by detection of Cyclin D1 mRNA. Cloning and Stem Cells. 6:58-66. Parker, M.H., E. Birck-Wilson, G. Allard, N. Masiello, M. Day, K.P. Murphy, V. Paragas, S. Silver and M.D. Moody (2004). Purification and characterization of a recombinant version of human alpha-fetoprotein in the milk of transgenic goats. Protein Expression & Purification. 38: 177-183. Singer, L.A., M.S.A. Kumar, W. Gavin, and S.A. Ayres. (2004). Predicting the onset of parturition in the goat by determining progesterone levels by enzyme immunoassay. Small Ruminant Research 52: 203-209 Baruah, G.L., D. Couto and G. Belfourt. (2003). A Predictive Aggregate Transport Model for Microfiltration of Combined Macromolecular Solutions and Poly-Disperse Suspensions: Testing Model with Transgenic Goat Milk. Biotechnology Progress. 19:1533-1540. Herrmann, L.M., W.P. Cheevers, T.C. McGuire, D.S. Adams, M.M. Hutton, W.G.Gavin and D.P. Knowles. (2003). Competitive-inhibition enzyme-linked immunosorbent assay for detection of serum antibodies to caprine arthritis-encephalitis virus: diagnostic tool for successsful eradication. Clinical and Diagnostic Laboratory Immunology 10:267-271. Honaramooz, A., E. Behboodi, S.O. Megee, S.A. Overton, H. Galantin-Homer, Y. Echelard and I. Dobrinski. (2003). Fertility and germline transmission of donor haplotype following germ cell transplantation in immunocompetent goats. Biology of Reproduction. 69:1260-1264. Honaramooz, A., E. Behboodi, S. Blash, S. O. MeGee, and I. Dobrinski. (2003). Germ Cell Transplantation in Goats. Molecular Reproduction and Development 64:422-428. Konkle, B., K. Bauer, R. Weinstein, A. Greist, H. Holmes, and J. Bonfiglio (2003). Use of Recombinant Human Antithrombin (AT) in Patients with Congenital AT Deficiency Undergoing Surgical Procedures. Transfusion 43: 390-4. Echelard, Y. and H. Meade (2002). Toward a new Cash Cow. Nature Biotechnology. 20 (9) :881-882. Gavin, W. (2002). Assisted Reproductive Technologies and the Production of Biotherapeutics. Proceedings of the Third Annual Tufts Animal Expo Educational Conference 3:61. Stowers, A.W., L.H. Chen, Y.L. Zhang, M.C. Kennedy, L.L. Zou, L. Lambert, T.J. Rice, D.C. Kaslow, A. Saul, C.A. Long, H. Meade and L.H. Miller. (2002). A recombinant vaccine expressed in the milk of transgenic mice protects Aotus monkeys from a lethal challenge with Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America. 99(1):339-344. Behboodi, E., W. Groen, M.M. Destrempes, J.L. Williams, C. Ohlrichs, W.G. Gavin, D.M. Broek, C.A. Ziomek, D.C. Faber, H.M. Meade and Y. Echelard. (2001). Transgenic production from in vivo-derived embryos: Effect on calf birth weight and sex ratio. Molecular Reproduction & Development September; 60(1):27-37. Gavin, W. (2001) The Future of Transgenics. Regulatory Affairs Focus. 6: 13-19. Click here to download an Adobe Acrobat file of William Gavin's paper titled "The Future of Transgenics" Copyright 2001 by the Regulatory Affairs Professionals Society (RAPS). Posted with permission on www.transgenics.com. Reprinted from the May 2001issue of Regulatory Affairs Focus. This article may not be published, reposted or redistributed without express permission from RAPS and payment of appropriate fees when applicable. To obtain such permission, send a message to acrompton@raps.org.   Han,Y., M. Meintjes, K. Graff, R. Denniston, L. Zhang, R. Godke and C. Ziomek. (2001). Caprine offspring born from fresh and frozen-thawed in vitro-produced embryos. The Veterinary Record. 149:714-716. Levy, J.H., A. Weisinger, C.A. Ziomek and Y. Echelard. (2001). Recombinant antithrombin: Production and role in cardiovascular disorder. Seminars in Thrombosis & Hemostasis. 27(4):405-416. Ongeri, E.M., C.L. Bormann, R.E. Butler, D. Melican, W.G. Gavin, Y. Echelard, R.L. Krisher and E. Behboodi. (2001). Development of goat embryos after in vitro fertilization and parthenogenetic activation by different methods. Theriogenology. 55:1933-1945. Reggio, B.C., A.N. James, H.L. Green, W.G. Gavin, E. Behboodi, Y. Echelard and R. Godke. (2001). Cloned transgenic offspring resulting from somatic cell nuclear transfer in the goat: Oocytes derived from both follicle-stimulating, hormone-stimulated and nonstimulated abattoir-derived ovaries. Biology of Reproduction. 65:1528-1533. Ayres, S.L., S. Nims, C. Porter, C. Cammuso and W. Gavin. (2000) Evaluation of follicular development and early pregnancy in goats using transvaginal ultrasound. Proceedings of the 7th International Confernce on Goats. 1: 481. Blash, S., D. Melican and W. Gavin. (2000). Cryopreservation of epididymal sperm obtained at necropsy from goats. Theriogenology 54: 899 - 905. Cammuso, C., C. Porter, S. Nims, D. Gaucher, D. Melican, S. Bombard, N. Hawkins, A. O'Coin, C. Ricci, C. Brayman, N. Buzzell, C. Ziomek and W. Gavin. (2000) Hormonal induced lactation in transgenic goats. Animal Biotechnology. 11: 1-17. Echelard, Y., C.A. Ziomek and H.M. Meade. (2000) Expression of recombinant proteins in the milk of transgenic goats. Proceedings of the 7th International Confernce on Goats. 1: 25-29. Fulton, S. (2000). Roundup on bioprocess validation issues: transgenic animal production of biopharmaceuticals. Genetic Engineering News Jan 1 20:36 Graff, K.J., M. Meintjes, Y. Han, B.C. Reggio, R.S. Denniston, W.G. Gavin, C. Ziomek and R.A. Godke. (2000). Comparing follicle stimulating hormone from two commercial sources for oocyte production from out-of-season dairy goats. Journal of Dairy Science. 83: 484-487. Lu, W., T.G.K. Mant, J.H. Levy and J.M. Bailey. (2000) Pharmacokinetics of recombinant transgenic antithrombin in volunteers. Anesthesia and Analgesia. 90:531-534. Minnena, M.C., A.C.K. Chang, P.M. Jansen, Y.T.P. Lubbers, B.M. Pratt, B.G. Whittaker, F.B. Taylor, C.E. Hack and B. Friedman. (2000). Recombinant human antithrombin III improves survival and attenuates inflammatory reponses in baboons lethally challenged with Escherichia coli. Blood Feb 15; 95 (4): 1117-1123. Taneja, M., P.E.J. Bols, A. Van de Velde, J.C. Ju, D. Schreiber, M.W. Tripp, H. Levine, Y. Echelard, J. Riesen and X.Z. Yang. (2000). Developmental competence of juvenile calf oocytes in vitro and in vivo: Influence of donor animal variation and repeated gonadotropin stimulation. Biology of Reproduction 62(1): 206-213. Baguisi, A., E. Behboodi, D.T. Melican, J.S. Pollock, M.M. Destrempes, C. Cammuso, J.L. Williams, S.D. Nims, C.A. Porter, P. Midura, M.J. Palacios, S.L. Ayres, R.S. Denniston, M.L. Hayes, C.A. Ziomek, H.M. Meade, R.A. Godke, W.G. Gavin, E.W. Overström and Y. Echelard. (1999). Production of goats by somatic cell nuclear transfer. Nature Biotechnol. 17: 456-461. Graff, K.J., M. Meintjes, V.W. Dyer, J.B. Paul, R.S. Denniston, C. Ziomek and R.A. Godke. (1999). Transvaginal ultrasound-guided oocyte retrieval following FSH stimulation of domestic goats. Theriogenology 51: 1099-1119. Newton, D.L., D. Pollock, P. DiTullio, Y. Echelard, M. Harvey, B. Wilburn, J. Williams, H.R. Hoogenboom, J.C. Raus, H.M. Meade and S.M. Rybak. (1999). Antitransferrin receptor antibody-Rnase fusion protein expressed in the mammary gland of transgenic mice. Journal of Immunological Methods. 231: 159-167. Pollock, D.P., J.P. Kutzko, E. Birck-Wilson, J.L. Williams, Y. Echelard and H.M. Meade. (1999). Transgenic milk as a method for the production of recombinant antibodies. Journal of Immunological Methods. 231: 147-157. Van Patten, S.M., E. Hanson, R. Bernasconi, K. Zhang, P. Manavalan, E.S. Cole, J.M. McPherson and T. Edmunds. (1999). Oxidation of methionine residues in Antithrombin. Effects on biological activity and heparin binding. J. Biol. Chem. 274: 10268-10276. Ziomek, C. (1999). Validation strategies for biopharmaceuticals: viral risk minimization for transgenic proteins from milk. Genetic Engineering News Apr. 15: 54. Edmunds, T., S. Van Patten, J. Pollock, E. Hanson, R. Bernasconi, E. Higgins, P. Manavalan, C. Ziomek, H. Meade, J. McPherson and E. Cole. (1998). Transgenically produced human antithrombin: structural and functional comparison to human plasma-derived antithrombin. Blood Jun 15; 91(12): 4561-71. Meade, H. and C. Ziomek. (1998). Urine as a substitute for milk? Nat Biotechnol. Jan; 16(1): 21-2. Young, M.W., H. Meade, J. Curling, C. Ziomek, and M. Harvey. (1998). Production of recombinant antibodies in the milk of transgenic animals. Res Immunol. Jul-Aug; 149(6): 609-610. Ziomek, C.A. (1998). Commercialization of proteins produced in the mammary gland. Theriogenology 49: 139-144. Meade, H. (1997). The Dairy Gene. The Sciences 20-25. Echelard, Y. (1996). Recombinant protein production in transgenic animals. Current Opinion in Biotechnology 7: 536-540. Gutierrez, A., H. Meade, P. Ditullio, D. Pollock, M. Harvey, R. Jimenez-Flores, G. Anderson, J. Murray and J. Medrano. (1996). Expression of a bovine kappa-CN cDNA in the mammary gland of transgenic mice utilizing a genomic milk protein gene as an expression cassette. Transgenic Res. Jul; 5(4): 271-9. Gutierrez-Adan, A., E.A. Maga, H. Meade, C.F. Shoemaker, J.F. Medrano, G.B. Anderson and J.D. Murray. (1996). Alterations of the physical characteristics of milk from transgenic mice producing bovine kappa-casein. J-Dairy-Sci. May; 79(5): 791-9. Ziomek, C.A. (1996). Minimization of viral contamination in human pharmaceuticals produced in the milk of transgenic goats. Dev. Biol. Stand. 88: 265-268. Ebert, K., P. DiTullio, C. Berry, J. Schindler, S. Ayers, T. Smith, L. Pellerin, H. Meade, J. Denman and B. Roberts. (1994). Induction of human tissue plasminogen activator in the mammary gland of transgenic goats. Biotechnology Jul; 12(7): 699-702. DiTullio, P., S.H. Cheng, J. Marshall, R.J. Gregory, K.M. Ebert, H.M. Meade and A.E. Smith. (1992). Production of cystic fibrosis transmembrane conductance regulator in the milk of transgenic mice. Bio/Technology 10(1): 74-77. Roberts, B., P. DiTullio, J. Vitale, K. Hehir and K. Gordon. (1992). Cloning of the goat b-casein-encoding gene and expression in transgenic mice. Gene 121: 225-262. Denman, J., M. Hayes, C. O'Day, T. Edmunds, C. Bartlett, S. Hirani, K.M. Ebert, K. Gordon and J.M. McPherson. (1991). Transgenic expression of a variant of human tissue-type plasminogen activator in goat milk: purification and characterization of the recombinant enzyme. Bio/Technology 9: 839-843. Ebert, K.M., J. Selgrath, P. DiTullio, J. Denman, T.E. Smith, M.A. Memon, J.E. Schindler, G.M. Monastersky, J.A. Vitale and K. Gordon. (1991). Transgenic production of a variant of human tissue-type plasminogen activator in goat milk: Generation of transgenic goats and analysis of expression. Bio/Technology 9: 835-838. Pittius, C.W., L. Hennighausen, E. Lee, H. Westphal, E. Nicols, J. Vitale and K. Gordon. (1988). A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice. Proc. Natl. Acad. Sci. 85: 5874-5878. Gordon, K., E. Lee, J.A. Vitale, A.E. Smith, H. Westphal and L. Hennighausen. (1987). Production of human tissue plasminogen activator in transgenic mouse milk. Bio/Technology 5: 1183-1187.   Abstracts: Melican, D., S. Blash and W. Gavin. (2008) Introducing New Genetics Into A Closed Biosecure Herd of Dairy Goats. Reproduction, Fertility and Development. 20 (1): 185. Altbuch, J., N. Buzzell, D. Melican, M. Schofield and W. Gavin. (2006) The induction of parturition in dairy goats and the outcome of kidding events. Theriogenology. 66 (3): 676-677. Ayres, S., M. Kumar, N. Buzzell, Q. Zhang, K. Baldwin and W. Gavin. (2006) Progesterone levels in goats using norgestomet implants as part of an estrous synchronization, superovulation protocol during the breeding season. Theriogenology. 66 (3): 681. Melican, D., N. Hawkins and W. Gavin. (2006) Generating a herd of transgenic dairy goats by somatic cell nuclear transfer. Reproduction, Fertility and Development. 18 (1,2): 139. He, S., D. Plant, S. Bischoff, W. Gavin, D. Melican and C.L. Keefer. (2005). Expression of pluripotency-determining factors Oct-4 and Nanog in preimplantation goat embryos. Presented at the International Embryo Transfer Society Annual Meeting in Copenhagen, Denmark. Reprod Fert Dev. 17 (1,2): 203. Simioni, P., E. Cozzi, M. Boldrin, F. Calabrese, S. Gavasso, M. Seveso, G. Tognin, N. Baldan, Y. Echelard, T. Rice, G. Thiene, A. Pagnan and E. Ancona (2005) Long-Term Treatment With High-Dose Recombinant Human Antithrombin Does Not Prevent Acute Hemoral Rejection In Primate Recipients Of Porcine Xenografts. International Society of Thrombosis & Hemostasis, Sydney, Australia August 2005. Behboodi, E., S.L. Ayres, E. Memili, M. O'Coin, L.H. Chen, H.M. Meade and Y. Echelard. (2004). Health and reproductive profiles of nuclear transfer goats producing the MSP1-42 malaria antigen. Proceedings of the Annual Conference of the International Embryo Transfer Society. 16 (1,2): 29. Butler, R.E., D. Melican, N. Hawkins, T. Jellerette, S. Nims, K. Graslie and W. Gavin. (2004). Effects of cycloheximide on caprine somatic cell nuclear transfer embryo and fetal development. Proceedings of the Annual Conference of the International Embryo Transfer Society. 16 (1,2): 31. Echelard, E., E. Memili, S.L. Ayres, M. O'Coin, L.H. Chen, H.M. Meade and E. Behboodi. (2004). Comparison of the developmental potential of caprine nuclear transfer embryos derived from in vitro and in vivo matured oocytes. Proceedings of the Annual Conference of the International Embryo Transfer Society. 16 (1,2): 36. Herrick, J.R., E. Behboodi, E. Memili, S. Blash, Y. Echelard and R.L. Krisher. (2004). Effect of macromolecule supplementation during in vitro maturation on the developmental competence of goat oocytes. Proceedings of the Annual Conference of the International Embryo Transfer Society. 16 (1,2): 314. Kowal-Vern, A., P. Bourdon, J. Ortegel, B. Latenser and L. Casey (2004). Antithrombin & Cytokines Diffuse Into Peritoneal Fluid in Burn Patients with Abdominal Compartment Syndrome. Shock Society, Halifax, Nova Scotia June 5-8 2004. Melican, D., R. Butler, N. Hawkins, S. Nims, N. Buzzel, T. Jellerette and W. Gavin. (2004). Estrus synchronization of dairy goats utilized as recipients for caprine nuclear transfer embryos. Proceedings of the Annual Conference of the International Embryo Transfer Society. 16 (1,2): 58. He, S., D. Pant, S. Bischoff, D. Melican, W. Gavin and C. Keefer. (2004). Expression of Embryonic Stem Cell (ESC) Markers in Preimplantation Goat Embryos. Presented at the Society for Study of Reproduction Annual Meeting in Vancouver, British Columbia, Canada. Biol Reprod. 212. Memili, E., E. Behboodi, M. O'Coin, H.M. Meade and Y. Echelard. (2004). Epigenetic characteristics of bovine and caprine embryos and donor cells used for nuclear transfer. Proceedings of the Annual Conference of the International Embryo Transfer Society. 16 (1,2): 60. Nims, S., D. Melican, T. Jellerette, R. Butler and W. Gavin. (2004). Effect of cytochalasin B treatment on vitrification of caprine parthogenic blastocysts. Proceedings of the Annual Conference of the International Embryo Transfer Society. 16 (1,2): 114. Tait, R.C., B. Konkle, K. Bauer, J. Bonfiglio, G. Dolan, J. Frieling, A. Greist, H. Holmes, M. Makris, M. Morfini, P. Noonan, J. Streisand, R. Weinstein, I. Walker and Y. Echelard (2004). Clinical Application of Recombinant Human Anti-thrombin (AT) in Patients with Hereditary Deficiency. German Society Thrombosis and Hemostasis, Hamburg, Germany, February 2004. Von Depka, M., D. Shaffer, F. Baudo, C. Shiach, J. Frieling, J. Bonfiglio and GTC rhAT Study Group. Safety and Efficacy of Prophylactic Intravenous Administration of Recombinant Human Antithrombin (rhAT) to Hereditary AT Deficient Patients in High-risk Situations. American Society of Hematology, San Diego, CA December 2004. Behboodi, E., E. Memili, S.L. Ayres, M. O'Coin, L.H. Chen, H.M. Meade, and Y. Echelard. (2003). Application of embryo cloning to the generation of transgenic founder goats. Theriogenology 59:237. Buzzell N., S. Blash, M. Cutler, D. Melican, J. Jameson, P. Flanagan, M. Olson and W. Gavin. (2003). Effects of short-term nutritional priming and multiple superovulation regimes on superovulated dairy goats. Presented at the American Society of Animal Science Annual Meeting in Phoenix, Arizona. J Anim Sci. 81 (1): 126-127. Butler, R.E., D. Melican, N. Hawkins, L. Chen, E. Hayden, M. Picarella, and W. Gavin. (2003). Production of transgenic goats by somatic cell nuclear transfer using transfected goat adult skin cells. Theriogenology 59:240. Destrempes, M.M., K.T. Rapiejko, J.L. Williams, L.H. Chen, E. Hayden, H. Liem, M. Picarella Stein, M.F. Shen, H.M. Meade, and Y. Echelard. (2003). Screening transgenic primary cell lines prior to use for somatic cell nuclear transfer. Theriogenology 59:245. Flanagan, P., D. Gaucher, K. Silberman, J. DeGloria and W. Gavin. (2003) Incidence of mastitis in first lactation dairy goats. National Mastitis Council Annual Meeting Proceedings. Gaucher, D., K. Silberman, J. DeGloria, W. Gavin and P. Flanagan. (2003) The distribution and seasonality of bacterial organisms cultured from early lactation goat milk.National Mastitis Council Annual Meeting Proceedings. Gavin, W., R. Butler, N. Hawkins, L.H. Chen, E. Hayden, M. Picarella, and D. Melican. (2003). Comparison of enucleation methods for the production of transgenic dairy goats by somatic cell nuclear transfer. Theriogenology 59:254. Melican, D., S. Blash, and W. Gavin. (2003). Caprine in vitro fertilization utilizing cryopreserved epididymal sperm from a 4-month-old transgenic buck. Theriogenology 59:455. Memili, E., E. Behboodi, S.A. Overton, M. O'Coin, A. Zahedi, H.M. Meade, and Y. Echelard. (2003). Synchronization of goat fibroblast cells at quiescent stage and determination of their transition from G0 to G1 by detection of cyclin D1 mRNA. Theriogenology 59:274. Richards, S., K. Welch, B. Noyst, J. Bonfiglio, J. Frieling, J. Streisand and E. Cole (2003). Assessment of Immunogenicity of Recombinant ATIII in Human Clinical Studies. Annals of Hematology 82 (Suppl 1) S72. (Poster presentation German Society Thrombosis and Hemostasis, Innsbruck, Austria, Feb 2003). Tait, R.C., B. Konkle, K. Bauer, J. Bonfiglio, G. Dolan, J. Frieling, A. Greist, H. Holmes, M. Makris, M. Morfini, B. Noonan, J. Streisand, R.Weinstein, I. Walker and Y. Echelard. (2003). Clinical Application of Recombinant Human Antithrombin (AT) in Patients with Hereditary Deficiency. Annals of Hematology 82 (Suppl 1) S84. (Poster presentation German Society Thrombosis and Hemostasis, Innsbruck, Austria, Feb 2003). Ziomek, C., J. Kutzko, L. Sherman, W. Gavin, C. Hendry, M. Hayes and E. Cole (2003). Viral and Prion Safety of Recombinant Human Antithrombin. Annals of Hematology 82 (Suppl 1) S95. (Poster presentation, German Society Thrombosis and Hemostasis, Innsbruck, Austria, Feb 2003). Behboodi, E., S.L. Ayres, B.C. Reggio, M.D. O'Coin, W.G. Gavin, R.S. Denniston, A.M. Landry, H.M. Meade and Y. Echelard. (2002). Pregnancy profile and health status of goats derived by somatic cell nuclear transfer. Theriogenology 57:395. Chen, L.H., E. Behboodi, B.C. Reggio, M.F. Shen, M.D. O'Coin, M.M. Destrempes, M.J. Sansinena, S.D. Nims, R.S. Denniston and H.M. Meade. (2002). Generation of transgenic goats from transfected fibroblast cell lines for the production of a malaria vaccine antigen. Theriogenology 57:777. Echelard, Y., M.M. Destrempes, J.A. Koster, C. Blackwell, W. Groen, D. Pollock, J.L. Williams, E. Behboodi, J. Pommer and H.M. Meade. (2002). Production of recombinant human serum albumin in the milk of transgenic cows. Theriogenology 57:779. Gaucher, D., P. Flanagan, K. Silberman, C. Porter, J. DeGloria and W. Gavin. (2002) Using bacterial culture surveillance to evaluate mastitis levels in fresh does. National Mastitis Council Annual Meeting Proceedings. Melican, D., S. Blash, J. Jameson and W. Gavin. (2002). 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